Photo CompetitionHurry up! There's an amazing photo competition. Deadline 30.09.2020
Please click here for further information.
Manuscript in arXivPersistence-Speed Coupling Enhances the Search Efficiency of Migrating Immune Cells
M. Reza Shaebani, Robin Jose, Ludger Santen, Luiza Stankevicins, Franziska Lautenschläger.
Paper accepted in Frontiers in Cell and Developmental Biology, section Molecular and Cellular OncologyCorrelative Fluorescence and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin
Indra Navina Dahmke, Patrick Trampert, Florian Weinberg, Zahra Mostajeran, Franziska Lautenschlaeger, Niels de Jonge.
Franziska Lautenschläger has been appointed as a full professor at University of Saarland.Prof. Dr. Franziska Lautenschläger is a civil servant now.
WelcomeWe welcome Galia Magela Montalvo Bereau as a new PhD student in a joint project with Dr. Bin Qu.
On 175 days in the anniversary year of DPG, Franziska Lautenschläger was among the interesting physicists who were introduced with a post on Instagram in regards with " 175 Inspirierende " for the physicists who today or in their time inspire or have inspired other people or even society as a whole through their field of activity.
DPG 175 years article link
Welcome Dr.Rodha HawkinsDr. Rodha Hawkins from Department of Physics and Astronomy, University of Sheffield,UK will be spending a week in our lab.
Franziska Lautenschläger`s interview aired on mdr.de radio
Reports published on University of Saarland portal, German Radio(MDR) and Ärzte Zeitung regarding recent paper on "Deterministic actin waves as generators of cell polarization cues"University of Saarland article link
Ärzte Zeitung link
Welcome Galia Magela Montalvo BereauWe welcome Galia Magela Montalvo Bereau as a new member of our lab.
Paper PublishedDeterministic actin waves as generators of cell polarization cues
Luiza Stankevicins, Nicolas Ecker, Emmanuel Terriac, Paolo Maiuri, Rouven Schoppmeyer, Pablo Vargas, Ana-Maria Lennon-Duménil, Matthieu Piel, Bin Qu, Markus Hoth,Karsten Kruse and Franziska Lautenschläger. PNAS December 27, 2019, https://doi.org/10.1073/pnas.1907845117
Cell Physics 2019Our lab members attended Cell Physics conference in Saarbrucken, 9th Oct - 11th Oct 2019.
Franziska Lautenschläger gave a talk on the topic "Vimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus".
Daniel Flormann gave a talk on "Structural analysis of the actin cortex and its correlation to cell mechanics in adhered and suspended states"
Christoph Anton, Divyendu Goud Thalla, Doriane Vesperini, Emmanuel Terriac, Kevin Kaub, Lucina Kainka and Zahra Mostajeran presented posters.
Zahra Mostajeran won 2nd place for her poster in the Cell Physics conference 2019.
POC 2019Franziska Lautenschläger and Lucina Kainka will be attending the 10th Annual Symposium "Physics of Cancer" taking place from September 25 - 27, 2019 at the University of Leipzig, Germany.
Franziska Lautenschläger will give a talk on the topic "Vimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus".
Lucina Kainka presented a poster on "Development of microtentacles upon wearing of the actin cortex".
Open PhD-PositionThere's an open PhD position in our lab.
The research topic will be "Therapeutic approach to improve migration of cytotoxic T lymphocytes in 3D" .
Please click here for further information. The application deadline is Sep 30, 2019.
LabdayWe had group sessions for conceptualising new project ideas followed by climbing activities & BBQ .
Manuscript in bioRxivVimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus
Luiza Da Cunha Stankevicins, Marta Urbanska, Daniel AD Flormann, Emmanuel Terriac, Zahra Mostajeran, Annica K.B. Gad, Fang Cheng, John E Eriksson, Franziska Lautenschlaeger.
CongratulationsDaniel Flormann won 2nd place in Photo competition 2019 of the SFB 1027.
Paper PublishedVimentin Intermediate Filament Rings Deform the Nucleus During the First Steps of Adhesion
Emmanuel Terriac, Susanne Schütz, Franziska Lautenschläger. Front. Cell Dev. Biol. 17 June 2019, https://doi.org/10.3389/fcell.2019.00106
Divyendu Goud Thalla, Doriane Vesperini , Franziska Lautenschläger and Zahra Mostajeran attended 11TH EUROPEAN MEETING ON INTERMEDIATE FILAMENTS AND COST ACTION EUROCELLNET MEETING in Turku, Finland from 9th to 11th June 2019
Franziska Lautenschläger gave a talk on "Vimentin in mechanics and migration of immune cells".
Divyendu Goud Thalla, Doriane Vesperini and Zahra Mostajeran presented posters on "Influence of extracellular vimentin on cell migration and adhesion" , "Vimentin intermediate filaments rings deform nucleus during the first steps of adhesion" and "The influence of Vimentin on actin dynamics" respectively.
Poster competition: "Vimentin intermediate filaments rings deform nucleus during the first steps of adhesion" poster by Emmanuel Terriac, Doriane Vesperini, Susanne Schütz and Franziska Lautenschläger got Second place.
Our lab members attended DPG Spring Meeting in Regensburg, 31 March - 5 April 2019Talks given:
How to survive a tenure track and young kids — Franziska Lautenschläger
Cytoskeletal organization in polar cells and interactions between different components — Carsten Baltes
The structure and mechanics of the cellular cortex before, during and after adhesion — Daniel Flormann
A microfluidic method to sort capsules and cells according to their size and deformability — Doriane Vesperini
The influence of vimentin on actin dynamics — Zahra Mostajeran
Influence of extracellular vimentin on cell migration — Divyendu Goud Thalla
Vimentin intermediate filaments rings deform nucleus during the first steps of adhesion — Emmanuel Terriac
Dynamic properties of actin cortex depend on the adhesion state of cells — Kevin Kaub
Formation of Microtentacles — Lucina Kainka
Automated tracing algorithm for scanning electron microscopy images of the actin cortex — Moritz Schu
Divyendu Goud Thalla, Doriane Vesperini , Kevin Kaub and Lucina Kainka attended CIRCLE MEETING 2019(27-03-2019 to 29-03-2019) organized in Saarland UniversityKevin Kaub gave a talk on "Influence of myosin, Arp2/3- and formin-inhibition on dynamics of cortical actin in different states of cellular adhesion".
Divyendu Goud Thalla and Lucina Kainka presented posters on "Influence of extracellular vimentin on cell migration and adhesion" & "Formation of Microtentacles" respectively.
Photo CompetitionHurry up! There's an amazing photo competition. Deadline 31.05.2019
Please click here for further information.
Franziska Lautenschläger`s interview published in Journal of Cell Science(2019)Jun.-Prof. Dr. Franziska Lautenschläger was interviewed by Manuel Breuer, Features & Reviews Editor at Journal of Cell Science. It got published in a SPECIAL ISSUE: RECONSTITUTING CELL BIOLOGY.
Click here to read the interview.
Paper PublishedWe are happy that the paper Quantitative analysis of F-actin alterations in adherent human mesenchymal stem cells: Influence of slow-freezing and vitrification-based cryopreservation is accepted by PLOS One journal.
Welcome Doriane VesperiniWe welcome Doriane Vesperini as a new postdoctoral researcher of our lab.
Daniel Flormann gave a talk on "How to give a talk" as a part of seminar within +Mint lecture on November 9th at Saarland University
Zahra Mostajeran presented a poster on "Measuring the dynamics of the actin filaments by FRAP in cells with a different amount of vimentin" on PhD Day at Saarland University on November 14th
Jun. Prof Franziska Lautenschläger, Daniel Flormann and Divyendu Goud Thalla attended "Cuban-German Graduate School in Cellular-Biophysics" from October 1st to October 5th at University of HavanaFranziska Lautenschläger gave talks on:
1) Molecular Motors
2) Structure and dynamics of the cytoskeleton
Daniel Flormann gave talks on:
1) Cell physics, cytoskeleton and microscopy techniques
2) Cell physics, dynamics and mechanics
Divyendu Goud Thalla and Zahra Mostajeran attended IF meeting from 12th to 13th Oct at Institute of Molecular and Cellular Anatomy, University Hospital of RWTH Aachen UniversityDivyendu gave a talk on his PhD project "Influence of extracellular vimentin in cell migration".
Zahra gave a talk on her PhD project "Measuring the dynamics of the actin filaments by FRAP in cells with a different amount of vimentin".
Jun. Prof Franziska Lautenschläger attended "Schiemann Symposium at Max Plack Society meeting" in Berlin on October 25thFranziska Lautenschläger gave talk on "Aspects of cell migration".
Paper accepted for publication in Cells JournalTitle: "Vimentin diversity in health and disease"
Author(s): Frida Danielsson, McKenzie Kirsten Peterson, Helena Caldeira Araújo, Franziska Lautenschläger, Annica Karin Britt Gad
Moritz Schu attended Summer School at University of coimbre on September 12thHe gave a talk on "Machine learning: Prediction of protein protein interactions".
Jun. Prof Franziska Lautenschläger and Emmanuel Terriac will be attending "Physics of Cells: From Biochemical to Mechanical" conference at Harrogate, UK from Sep 3 - 7, 2018She will give a talk on "Spiral actin waves as modulators of amoeboid cell movement" and Emmanuel Terriac will present a poster on “Cell cortex structure and dynamics before, during and after adhesion”.
Welcome Madalena FreitasMadalena Freitas will be trained on confocal microscopy in our lab to conduct her project investigations.
Paper accepted for publication in Biomacromolecules JournalTitle: "Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization and Investigation of Mucus-Particle Interactions"
Author(s): Ho, Duy-Khiet; Frisch, Sarah; Biehl, Alexander; Terriac, Emmanuel; De Rossi, Chiara; Schwarzkopf, Konrad; Lautenschlaeger, Franziska; Loretz, Brigitta; Murgia, Xabier; Lehr, Claus-Michael
BioInterface meeting INMDaniel Flormann and Kevin Kaub gave talk on "Cell cortex structure and dynamic before, during and after adhesion" during BioInterface meeting at INM on June 18th.
Jun. Prof Franziska Lautenschläger will be attending "Intermediate Filaments as the Platform to Underpin the Social Network of Cells and Tissues" conference in Italy from June 24th - 29th, 2018She will be a panel speaker and presenter of both a poster and a oral presentation on "The role of vimentin in leukocyte amoeboid migration" at the conference.
Zahra Mostajeran will be attending "Generation And Control of Forces In Cells" workshop from June 22nd to 29thZahra Mostajeran will give a talk on “ Measuring dynamics of the actin filaments by FRAP in cells with a different amount of vimentin” at NORDITA (Nordic Institute for Theoretical Physics) in Stockholm University and Royal Institute of Technology.
CongratulationsZahra Mostajeran won third place in Photo competition 2018.
Welcome BenjaminBenjamin Flores has joined our lab for an internship. He will work on AFM measurements with Daniel Flormann.
Lucina Kainka attended Summercamp des SFB 1027 at Bad Münster am Stein from June 26th to 29thShe presented a poster on "Formation of microtentacles upon weakening of the actin cortex".
Welcome Moritz SchuWe welcome Moritz Schu as a new member of our lab. He will do his Bachelor Project with us.
Jun. Prof Franziska Lautenschläger attended seminar at Niels Bohr Institute, Copenhagen on June 4thShe gave a talk on the topic "The cytoskeleton in cellular functions".
Kevin Kaub and Lucina Kainka attended Circle Meeting Biophysics 2018, Francis Crick Institute, London from June 7th to 8thKevin Kaub presented a poster on "Influence of myosin II, Arp2/3 and formin-inhibition on dynamics of cortical actin in adherent and suspended cells" and Lucina Kainka gave talk on "Formation of microtentacles upon weakening of the actin cortex".
Divyendu Thalla attended IF meeting from May 15th to 17th at Institute for X-Ray Physics, Georg-August-Universität Göttingen, GermanyHe gave a talk on Influence of extracellular vimentin in cell migration.
Zahra Mostajeran attended "Scientific Talks" workshopZahra Mostajeran attended workshop called “ scientific talks” on May 22nd and 29th in Saarland University campus Homburg.
Jun. Prof Franziska Lautenschläger attended Tag der offenen Tür at Universität Des Saarlandes on May 26thShe gave a talk on "Krebszellen unter dem Mikroskop".
Day of Open Doors26 May 2018 (Physik C 6.3)
Please click here for further information.
Zahra Mostajeran gave a talk on "Measuring the dynamics of the actin filaments by FRAP in cells with a different amount of vimentin" as a part of her PhD seminar at INM on March 26th
Photo CompetitionHurry up! There's an amazing photo competition. Deadline 31.05.2018
Please click here for further information.
LabdayWe had talks from all our lab members followed by amazing social activities.
Welcome Doriane VesperiniWe welcome Doriane Vesperini as a new member of our lab. She will do her DAAD-Internship with us.
Paper acceptedWe are happy that the paper Red blood cell passage of small capillaries is associated with transient Ca2+-mediated adaptations is published by Frontiers in Physiology.
The authors are Jens G. Danielczok, Emmanuel Terriac, Laura Hertz, Polina Petkova-Kirova, Franziska Lautenschläger, Matthias W. Laschke and Lars Kaestner.
Welcome DivyenduWe welcome Divyendu Goud Thalla as a new PhD student of our lab.
PhD Position takenThe PhD position is now taken. We are happy to announce that we have found a suitable future member of our group. You will find more information soon.
Open PhD PositionThere's an open PhD position in our lab. Please click here for further information.
Welcome Daniel FlormannWe welcome Daniel Flormann as a new postdoctoral researcher of our lab.
Paper acceptedWe are happy that the paper Vimentin levels and serine 71 phosphorylation in the control of cell-matrix adhesions, migration speed and shape of transformed human fibroblasts was accepted for publication by Cells.
The authors are Emmanuel Terriac, Giovanna Coceano, Zahra Mavajian, Tijmen Hageman, Andreas Christ, Ilaria Testa, Franziska Lautenschläger, Annica Gad
Cell Physics conferenceThis year's cell physics conference will take place from October 11th to October 13th.
We moved to the INMWe moved to the Leibniz Institute for New Materials (Campus Saarbrücken, Building D2 2) in January 2017. New contact information is now available.
Open PhD-PositionThere will be an open PhD-Position beginning in 1st January 2017. The research topic will be "Extracellular vimentin in migration". Further information for applicants can be acquired by contacting Jun.-Prof. Lautenschläger.
Update: The PhD position is no longer available.
InternshipWe are happy about Sophie Geiger and Aaron Schneider to have successfully finished their internship in our workgroup
Elisabeth Schiemann KollegFranziska Lautenschläger has been recently accepted as a fellow in the Elisabeth Schiemann Kolleg of the Max Planck Society. For further information click here.
Welcome Zahra MostajeranWe welcome Zahra Mastojeran as a new member of our lab. She will do a training with us for six months.
Paper in SciencePublication ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death (M. Raab et al., Science 10.1126/science. aad7611 (2016).) now available.
Welcome Kevin KaubWe welcome Kevin Kaub as a new member of our lab. He will do his Bachelor's thesis with us.
New homepageA new homepage is online since 16.03.2016.