Publications
A low-cost alternative method of generating fibronectin micropatterned lines for cellular applications
Johanna Elisabeth Becher, Franziska Lautenschläger and Divyendu Goud Thalla Methods X June 3, 2023
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Amoeboid Cell Migration through Regular Arrays of Micropillars under Confinement
Zeinab Sadjadi, Doriane Vesperini, Annalena M. Laurent, Lena Barnefske, Emmanuel Terriac, Franziska Lautenschläger and Heiko Rieger Biophysical Journal December 6, 2022
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Distinct speed and direction memories of migrating dendritic cells diversify their search strategies
M. Reza Shaebani, Matthieu Piel, Franziska Lautenschläger Biophysical Journal September 30, 2022
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Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling
Ponnuswamy Mohanasundaram, Leila S Coelho Rato, Mayank Modi, Marta Urbanska, Franziska Lautenschläger, Fang Cheng, John E Eriksson PLOS Biology September 13, 2022
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Effects of vimentin on the migration, search efficiency, and mechanical resilience of dendritic cells
M. Reza Shaebani, Luiza Stankevicins, Doriane Vesperini,Marta Urbanska,Daniel A.D.Flormann,Emmanuel Terriac,Annica K.B.Gad,Fang Cheng,John E.Eriksson,Franziska Lautenschläger Biophysical Journal 2 September 2022
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Actin stabilization in cell migration
Carsten Baltes, Divyendu Goud Thalla, Uli Kazmaier and Franziska Lautenschläger Front. Cell Dev. Biol. 11 August 2022
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Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis
Divyendu Goud Thalla, Ashish Chand Rajwar, Annalena Maria Laurent, Johanna Elisabeth Becher, Lucina Kainka and Franziska Lautenschläger Front. Cell Dev. Biol., 18 July 2022
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Metastasising Fibroblasts Show an HDAC6-Dependent Increase in Migration Speed and Loss of Directionality Linked to Major Changes in the Vimentin Interactome
Caroline A. Evans, Hyejeong Rosemary Kim, Sarah C. Macfarlane, Poppy I. A. Nowicki, Carsten Baltes, Lei Xu, Jerker Widengren, Franziska Lautenschläger, Bernard M. Corfe and Annica K. B. Gad Int.J.Mol.Sci 10 February 2022
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Oscillatory Microrheology, Creep Compliance and Stress Relaxation of Biological Cells Reveal Strong Correlations as Probed by Atomic Force Microscopy
D.A.D. Flormann, C. Anton, M.O. Pohland, Y. Bautz, K. Kaub, E. Terriac, T.E. Schäffer, J. Rheinlaender, A. Janshoff, A. Ott and F. Lautenschläger Front. Phys 23 August 2021
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Role of Extracellular Vimentin in Cancer-Cell Functionality and Its Influence on Cell Monolayer Permeability Changes Induced by SARS-CoV-2 Receptor Binding Domain
Divyendu Goud Thalla, Philipp Jung, Markus Bischoff, Franziska Lautenschläger IJMS 12 July 2021
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Scanning electron microscopy preparation of the cellular actin cortex: A quantitative comparison between critical point drying and hexamethyldisilazane drying
Moritz Schu, Emmanuel Terriac, Marcus Koch, Stephan Paschke, Franziska Lautenschläger, Daniel A. D. Flormann. PLOS ONE 7 July 2021
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A novel universal algorithm for filament network tracing and cytoskeleton analysis
Daniel A. D. Flormann, Moritz Schu, Emmanuel Terriac, Divyendu Thalla, Lucina Kainka, Marcus Koch, Annica K. B. Gad, Franziska Lautenschläger. FASEB 9 April 2021
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Characterization of immune cell migration using microfabrication
Doriane Vesperini, Galia Montalvo1, Bin Qu, Franziska Lautenschläger. Biophysical Reviews 11 February 2021
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Persistence-speed coupling enhances the search efficiency of migrating immune cells
M. Reza Shaebani, Robin Jose, Ludger Santen, Luiza Stankevicins, and Franziska Lautenschläger. Phys. Rev. Lett. 4 December 2020
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Prestress and Area Compressibility of Actin Cortices Determine the Viscoelastic Response of Living Cells
Andrea Cordes, Hannes Witt, Aina Gallemí-Pérez, Bastian Brückner, Florian Grimm, Marian Vache, Tabea Oswald, Jonathan Bodenschatz, Daniel Flormann, Franziska Lautenschläger, Marco Tarantola, and Andreas Janshoff. APS physics August 6, 2020, https://doi.org/10.1103/PhysRevLett.125.068101
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Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin
Indra Navina Dahmke, Patrick Trampert, Florian Weinberg, Zahra Mostajeran, Franziska Lautenschläger and Niels de Jonge. Front. Cell Dev. Biol. June 30, 2020, https://doi.org/10.3389/fcell.2020.00521
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Highly coordinated mechanical motion mediated by the microtubule cytoskeleton is a pivotal element of de-novo symmetry breaking in hydra spheroids
Heike Sander, Aravind Pasula, Mathias Sander, Varun Giri, Emmanuel Terriac, Franziska Lautenschlaeger, Albrecht Ott. bioRxiv January 14, 2020, https://doi.org/10.1101/2020.01.14.906115
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Scanning electron microscopy preparation and analysis of the cell cortex ultrastructure
D. Flormann, M. Schu, E. Terriac, M. Koch, S. Paschke, F. Lautenschläger. bioRxiv January 7, 2020, https://doi.org/10.1101/2020.01.06.896761
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Deterministic actin waves as generators of cell polarization cues
Luiza Stankevicins, Nicolas Ecker, Emmanuel Terriac, Paolo Maiuri, Rouven Schoppmeyer, Pablo Vargas, Ana-Maria Lennon-Duménil, Matthieu Piel, Bin Qu, Markus Hoth,Karsten Kruse and Franziska Lautenschläger. PNAS December 27, 2019, https://doi.org/10.1073/pnas.1907845117
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Vimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus
Luiza Da Cunha Stankevicins, Marta Urbanska, Daniel AD Flormann, Emmanuel Terriac, Zahra Mostajeran, Annica K.B. Gad, Fang Cheng, John E Eriksson, Franziska Lautenschlaeger.
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Vimentin Intermediate Filament Rings Deform the Nucleus During the First Steps of Adhesion
Emmanuel Terriac, Susanne Schütz, Franziska Lautenschläger. Front. Cell Dev. Biol. 17 June 2019, https://doi.org/10.3389/fcell.2019.00106
Quantitative analysis of F-actin alterations in adherent human mesenchymal stem cells: Influence of slow-freezing and vitrification-based cryopreservation
Yannik Müllers, Ina Meiser, Frank Stracke, Iris Riemann, Franziska Lautenschläger, Julia C. Neubauer, Heiko Zimmermann PLOS One 2019, doi.org/10.1371/journal.pone.0211382.
Vimentin Diversity in Health and Disease
Frida Danielsson, McKenzie Kirsten Peterson, Helena Caldeira Araújo, Franziska Lautenschläger, Annica Karin Britt Gad. Cells 2018, 7(10), 147; doi:10.3390/cells7100147
Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization and Investigation of Mucus-Particle Interactions.
Ho, Duy-Khiet; Frisch, Sarah; Biehl, Alexander; Terriac, Emmanuel; De Rossi, Chiara; Schwarzkopf, Konrad; Lautenschlaeger, Franziska; Loretz, Brigitta; Murgia, Xabier; Lehr, Claus-Michael (2018). Biomacromolecules
Red blood cell passage of small capillaries is associated with transient Ca2+-mediated adaptations
Danielczok J.D., E. Terriac,L. Hertz, P. Petkova-Kirova, F. Lautenschläger, M. W. Laschke, L. Kaestner (2017).
Frontiers in Physiology 10.3389/fphys.2017.00979.
Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts.
Terriac, E., G. Coceano, Z. Mavajian, T. A. Hageman, A. F. Christ,
I. Testa, A. K. Gad, and F. Lautenschlager (2017). Cells 6(1).
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death.
M.Raab, M. Gentili, H. de Belly, H.R. Thiam, P. Vargar, A.J. Jimenez, F. Lautenschläger,
Raphaël Voituriez, A.M.. Lennon-Duménil, N. Manel, M. Piel (2016) Science 10.1126/science. aad7611
Myosin II Activity softens cells in suspension.
CJ.Chan, A.Ekpenyong, S.Golfier, W.Li, K.Chalut, O.Otto, J.Elgeti, J.Guck, F. Lautenschläger (2015) Biophysical Journal 108: 1856-1869
Actin Flows Mediate a Universal Coupling between Cell Speed and Cell Persistence.
P.Maiuri, J-F Rupprecht, S.Wieser, V.Ruprecht, O.Bénichou, N.Carpi, M.Coppey, S. De Beco, N.Gov, C-P.Heisenberg, C.Lage Crespo,
F.Lautenschäger, M.Le Berre, A-M.Lennon-Dumenil, M.Raab, H-R.Thiam, M.Piel, M.Sixt, R.Voituriez (2015) Cell 161(2): 374-386
Confinement in a non-adhesive environment induces fast amoeboid migration of slow mesenchymal cells.
Y-J.Liu, M. Le Berre, F.Lautenschläger, P.Maiuri, A.Callan Jones, T.Takaki, R.Voituriez and M.Piel (2015)
Cell 160(4): 659-672
Space Exploration by Dendritic Cells relies on maintenance of cell polarity and Myosin II activity by IP3 receptor.
P.Solanes, P.Vargas, M.Maurin, M-L Heuzé, F.Lautenschläger, P.Maiuri, E.Terriac,
M.Bretou, P.Launay, M.Piel and A-M.Lennon-Duménil (2015) The EMBO Journal
Methods for Two-Dimensional Cell Confinement.
M.l Le Berre, E. Zlotek-Zlotkiewicz, D. Bonazzi, F. Lautenschläger, M. Piel (2014) Methods in Cell Biology 121: 213-229
Microfabricated devices for cell biology: all for one and one for all.
F. Lautenschläger, M.Piel. (2013) Current Opinion in Cell Biology 25:116–124
Viscoelastic Properties of Differentiating Blood Cells Are Fate- and Function-Dependent.
A. Ekpenyong, G. Whyte, K. Chalut, S. Pagliara, F. Lautenschläger, C. Fiddler, S. Paschke, U. Keyser, E. Chilvers,
J. Guck. (2012) PLoS ONE 7(9): e45237.
Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells.
K. Chalut, M. Hoepfler, F. Lautenschläger, C J Chan, A. Ekpenyong, A. Martinez-Arias, J. Guck. (2012)
Biophysical Journal 103 (10): 2060-2070.
3D inverted colloidal crystals in realistic cell migration assays for drug screening applications.
J. da Silva, J, F. Lautenschläger, C.H.R. Kuo, , J. Guck, E. Sivaniah. (2011) Integrative Biology 3 (12): 1202-1206.
Detection of ‘plasmodium falciparum’ infected red blood cells by optical stretching.
J. Mauritz, T. Tiffert, R. Seears, M. Ziemienczuk, F. Lautenschläger, A. Esposito, V. Lew, J. Guck, C. Kaminski. (2010) Journal of Biomedical Optics (15): 030517.
Mechanical markers of attached and suspended mesenchymal stem cells.
J. Maloney, D. Nikova, F. Lautenschläger, R. Langer, J. Guck, K. Van Vliet. (2010) Biophysical Journal 99 (8): 2479-2487
Critical review: Cellular mechanobiology and amoeboid migration.
J. Guck, F. Lautenschläger, S. Paschke, M. Beil. (2010) Integrative Biology 99 (8): 2479-2487
Dual-beam laser traps in biology and medicine: when one beam is not enough.
G. Whyte , F. Lautenschläger, M. Kreysing, L. Boyde, A. Ekpenyong, U. Delabre, K. Chalut, K. Franze, J. Guck. (2010) Proceedings of the SPIE Volume 7762, pp. 77620G-77620G.
The regulatory role of cell mechanics for migration of differentiating myeloid cells.
F. Lautenschläger, S. Paschke, S. Schinkinger, A. Bruelle, M.Beil, J.Guck. (2009) Proceedings of the National Academy of Sciences 106 (37): 15696-15701.
Microfluidic integration of high power dual-beam laser traps for cell mechanical measurements.
F. Lautenschläger, J.Guck. (2009) International Symposium on Optomechatronic Technologies 409-412
The cavity-to-cavity migration of leukaemic cells through 3D honey-combed hydrogels with adjustable internal dimension and stiffness.
J. da Silva , F. Lautenschäger, E. Sivaniah, J. Guck. (2009) Biomaterials 31 (8): 2201-8.